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5 Moreover, alcohol metabolites contribute to lipid droplet accumulation in the pancreas, activate the AMPK signaling pathway involved in lipid metabolism, and enhance autophagy in acinar cells

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Playing a pivotal role in the transsulfuration pathway and redox regulation 2,3 and being linked to one-carbon metabolism, CBS produces cysteine, glutathione, as well as the gaseous transmitter hydrogen sulfide 4,5 (H 2 S)

In the course of the experiments, tert-butyl hydroperoxide (TBHP) was used to induce oxidative stress in annulus fibrosus cells (AFCs) and nucleus pulposus cells (NPCs)