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Retatrutide has a higher overall adverse event burden (6-10% discontinuation), partly because of the unique dysesthesia side effect at higher doses

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Pickard FC, Knig G, Tofoleanu F, Lee J, Simmonett AC, Shao Y, Ponder JW, Brooks BR (2016) Blind prediction of distribution in the SAMPL5 challenge with QM based protomer and pK a corrections

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