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Having a lack of intrinsic factor (IF) , a substance that binds to B12 so it can be absorbed into the bloodstream (5)
B6 (pyridoxine) Apart from its role in the folate cycle, B6 is required for amino acid metabolism and serves as a rate-limiting cofactor in the synthesis of several neurotransmitters, including dopamine, serotonin, -aminobutyric acid (GABA), noradrenaline, and melatonin

Chiu TY, Teng HC, Huang PC, Kao FJ, Yang DM
