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GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension

UV radiation is highly genotoxic but is also known as a significant prooxidant factor, which induces reactive oxygen species (ROS) generation by affecting cellular components directly or by means of photosensitization mechanisms 7 (Table 1)

It has also been observed that when H2O2-induced cervical cancer biopsies treated with EGCG (50 g/ml) suppress the activity of SOD and GPx by 38.54% and 57.04%, respectively