b12 injection sq or im subcutaneous vs.intramuscular b12 injections Subcutaneous (SC) and Intramuscular (IM) Injections– b12 injections sq or im

Drug Interactions Several common medications reduce B12 absorption: Metformin (diabetes) significant reduction in B12 absorption Proton pump inhibitors (Omeprazole, Pantoprazole) reduce stomach acid needed for absorption H2 blockers (Ranitidine, Famotidine) similar effect to PPIs Colchicine (gout) may reduce B12 absorption If you take any of these medications long-term, B12 supplementation is strongly recommended

analyzed the data and assisted in manuscript preparation

it works upstream, on an enzyme called nicotinamide N-methyltransferase (NNMT) that fat cells over-express when they become metabolically sluggish

Selected Literature Supporting B12 Research de Groot CP et al., Am J Clin Nutr 1999 Elderly absorption and dietary adequacy