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The presence of the fast calcium sensor Synaptotagmin 1 (SYT1) on the membrane of synaptic vesicles is thought to underlie rapid vesicle fusion with the presynaptic membrane at the majority of central synapses 47,48

10.1016/j.cell.2013.02.035 21 CantoC.Gerhart-HinesZ.FeigeJ

To stabilize themselves, they react with nearby molecules, damaging DNA, proteins, cell membranes and lipids in the process

Even though hyperoxia may seem harmless, it can have detrimental effects even at modest levels if prolonged, especially in critically ill patients
