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Description
With respect to ketone utilization, CYP2E1 is responsible for metabolism of acetone which is a product of the ketogenesis pathway

Androgen Network Modulation: LT decreased CYP11A1/CYP17A1 and elevated CYP19A1, showing upstream inhibition-downstream activation. LT also boosted -diversity, adjusted the F/B ratio, enriched Dubosiella / Muribaculum , and inhibited Lachnospiraceae and Alistipes

& Golan, D

oxPTMs might represent a promising avenue, as they may reflect both intrinsic beta-cell stress and immune activation
