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We produce Au 15 SG 13 (SG for glutathione) with atomic precision and functionalize it with a thiolated aminooxy moiety to impart protein carbonyl-binding properties
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In addition to oxidative base modifications, ROS attack on DNA can result in the formation of DNA strand breaks (DSBs)
Some studies have highlighted its role in the regulation of GPx activity and induction of metallothionein expression
