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GEMINI 1 and 2 phase III trials showed that tolebrutinib was not superior to teriflunomide in reducing relapses, but there was a reduction in 6-month confirmed disability progression, although this was not formally tested (80)
Tirzepatide offers similar benefits through a dual-action mechanism (Mounjaro, Zepbound)
That's what makes it so interesting to the scientific community
Recommended Assessment Tools Body Composition Analysis (Gold Standard): DEXA (Dual-Energy X-ray Absorptiometry) scanning provides precise body fat percentage, lean mass, and visceral fat measurements
