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This chronic low-grade inflammation is associated with elevated levels of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which are involved in cellular proliferation, immune evasion, and tumor survival
Consequently, grilling and pan-frying generate primarily aminoimidazoazarenes, while smoking at very high temperatures can produce both classes

[DOI] [PubMed] [Google Scholar] 19.Favilli F, Marraccini P, Iantomasi T, Vincenzini MT
