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In the first stage, each model was constrained to obtain an optimal fit to the gene expression signature of the cell line by solving a Mixed Integer Linear Programming problem, via the integrative Metabolic Analysis Tool (iMAT) 32,33

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Forty-three children admitted between 1985 and 1989 acted as controls

Another randomized double blind placebo controlled trial looked at the effects of oral glutathione on biomarkers of systemic oxidative stress in human volunteers
