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B12 and methylation can impact many biochemical pathways and affects your DNA replication, the rate at which we age, energy production, detoxification, mental health, and hormones

The fact that estrogens produce an alteration in GH secretion may be due to the affectation of the feedback mechanisms through which IGF-I acts on GHRH and SS, in this case extraordinarily diminished by these steroids [143]

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The absorption profile differs slightly, with potentially faster uptake but similar overall bioavailability