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Similarly, Selank is applied in investigations of anxiolytic signaling and immune-neuroendocrine interactions, often within GABAergic and cytokine-related pathways
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Nrf2 is also required for GCLM induction by 15d-PGJ 2 (Chen et al., 2006)
The preclinical evidence is robust, consistent, and mechanistically plausible, but the gap between rat sciatic nerve transection models and human diabetic neuropathy is significant
