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N Engl J Med 383:11171128
Emerging evidence indicates that reactivation of oncogenic signaling pathways is frequently accompanied by parallel reprogramming of metabolic networks, forming a coordinated dual-track mechanism of resistance driven by signaling-metabolism crosstalk [75]
A recent study in mature rat hippocampal neurons showed that l-carnitine and ALC protected the mitochondrial membrane potential and countered the decline in oxygen consumption rates and the rise in mitochondrial fragmentation provoked by A1-42 [81]
doi:10.3945/ajcn.114.091819
