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MSM pre-treatment before endurance exercise, which is a known trigger for ROS production, can attenuate protein oxidation, lipid peroxidation, creatine kinase, oxidized glutathione, and uric acid, and also increase total antioxidant capacity (5)
Research confirms that sleep deprivation significantly reduces antioxidant defenses including glutathione
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Researchers were not blinded to the experimental groups during in vivo treatments
