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In contrast, chronic or diabetic wounds often exhibit metabolic disturbances that are potentially characterized by excessive glycolysis coupled with suppressed oxidative phosphorylation or mitochondrial dysfunction, resulting in insufficient energy metabolism and exacerbated inflammatory responses

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L-Glutamine also promotes cell proliferation, osteogenic differentiation and fracture healing, exerts neuroprotective and cardioprotective effects, and inhibits osteoarthritis

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It is slightly soluble in water, with a maximum solubility around 1.6 mg/L [19]

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