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The present review also integrates developments through early 2025, including the discontinuation of the pegtarviliase program and the rebranding of CDX-6512 as SYNT-202, with corresponding updates from clinical trial data, regulatory announcements and pipeline disclosures

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Nevertheless, the C4H transcript level did not correlate with lignin accumulation, possibly due to the associations between the phenylpropanoid pathway and flavonoid or anthocyanin and coumarin metabolic pathways

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