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The present review also integrates developments through early 2025, including the discontinuation of the pegtarviliase program and the rebranding of CDX-6512 as SYNT-202, with corresponding updates from clinical trial data, regulatory announcements and pipeline disclosures

Nevertheless, the C4H transcript level did not correlate with lignin accumulation, possibly due to the associations between the phenylpropanoid pathway and flavonoid or anthocyanin and coumarin metabolic pathways
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