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Fletcher et al

Changes in the BBB associated with Alzheimer's disease primarily include endothelial abnormalities such as reactive gliosis, mitochondrial damage, alterations in the extracellular matrix, disrupted tight junctions, and both molecular and functional changes in astrocytes

The synthesis occurs predominantly in the presynaptic terminals of GABAergic neurons, where GABA is packaged into synaptic vesicles ready for release into the synaptic cleft during neurotransmission

avoid freeze thaw cycles Laboratory research only Not for human or clinical use Handled only by qualified personnel CAS Number: 42464-96-0 Molecular Formula: C7H9N3O Each batch undergoes internal analytical verification using chromatographic and spectrometric methods prior to lyophilisation