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This was consistent with the results from the sham group, which also demonstrated the improved anti-PD efficacy of Res-lips@Fe 3 O 4

For instance, analyzing the most recent TCGA multidimensional omics data revealed that multiple iron-related genes ( e.g., scavenger receptor class A member 5 (SCARA5), erythroferrone (ERFE), lipocalin 2, transferrin receptor 2 (TFR2), solute carrier family 11 member 1 (SLC11A1), and cytochrome B reductase 1 (CYBRD1)) were dysregulated in different cancers, and this outcomes may be associated with aberrant DNA methylation[112]

Elevated heme oxygenase 1 and ferritin levels observed during this process were reduced by the ferroptosis inhibitor UAMC-3203

Under nutrient-deprived conditions, cancer cells depend on optimal metabolic pathways for survival