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Various disease models also revealed the accumulation of 15-LOX/PEBP1 complex resulted in elevated oxidized PEs and ferroptosis [137]

Int J Psychiatry Clin Pract

2) pyruvate / oxoglutarate decarboxilation to thiamine phyrophosphate by pyruvate / oxoglutarate dehydrogenase (PDH / OGDH) that is required for the formation of acetyl / succinyl coenzyme A (CoA)