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and Cotter T
For example, ROS drive hypoxia-inducible factor 1 (HIF1) mediated GLUT1 expression, hexokinase activity, and resultant glycolysis in response to low oxygen tension as part of the angiogenic response (27) The co-localization of neutrophil phosphofructokinase 2 with NOX2 leads to its activation, resulting in NADP+ production as its byproduct, facilitating an enhanced glycolytic rate
Pateiro, M., Gomez, B., Munekata, P
Hyperglycemia and dyslipidemia promote depressive symptoms by increasing systemic inflammation and reducing brain levels of serotonin (5-hydroxytryptamine, 5-HT) (Cai et al., 2022
