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Int J Oncol 2017

However, it is essential to note that while the peptide appears to elevate the expression of beta(3)-AR, it may not act directly through the beta(3)-AR to induce its potential lipolytic action

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Deletion of the insulin receptor in a mouse model showed decreased blood glucose levels in response to IGF-1 (112), whereas in vivo reduction of serum IGF-1 by 80% impaired glucose tolerance (113)
