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Another limitation is that we did not design the forced choice method to establish a threshold

At the molecular level, interactions between VEGF and VEGFR-mediated signal transduction, promote reprogramming of specific gene expression in endothelial cells, including upregulated expression of several proteins encompassing the procoagulant tissue factor, proteins associated with the fibrinolytic pathway, MMPs and a number of anti-apoptotic factors (90, 91)

Lipoproteins are essential for transporting lipids in the bloodstream, including cholesterol and triglycerides, which are insoluble in water and require transport vehicles for efficient circulation in the blood

There are currently no dedicated medicines that target the reduction of Lp(a) concentrations and available lipid-lowering treatment can only modify the concentration of this parameter to a certain extent (2030%)