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ClinicalTrials.gov 2
What Causes Under-Eye Circles and Why Most Treatments Fail Under-eye circles are not a single condition
3.8 Clostridium in scleroderma As an immune-mediated rheumatic disease, SSc, or scleroderma, causes fibrosis of the skin and internal organs as well as vascular disease (225)
This study was approved by the local Ethics Committee
