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In the DiYA cohort, 93/2063 (4.5%) had both RBA-GADA and ECL-GADA, 32 (1.6%) were positive for RBA-GADA alone, while only 5 (0.2%) had ECL-GADA alone
doi: 10.4161/cc.7.24.7231
This reliance on correlative evidence from disease contexts has reduced CHAC enzymes to mere stress markers and overlooked their potential as dynamically regulated metabolic integrators
Dysregulation of innate immunity is hypothesized to be a potent driver of MDS
