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Dexpramipexole, the R(+) enantiomer of pramipexole, for the potential treatment of amyotrophic lateral sclerosis
Another severe NLS mutation (P525L) provided modestly better rescue of splicing changes, but was still far less efficient than wild-type FUS/TLS
A comprehensive survey of the prolific literature within this field is beyond the scope of this review, but it is noteworthy, that HIV-associated body wasting is a licensed indication for GH treatment in the USA
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