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Because of the small numbers of patient studied, it is not possible to evaluate synergistic effects with any of these agents

Methods for transplantation of human cerebral organoids into the adult mouse brain have been established, and organoids demonstrate neuronal differentiation, axonal pathfinding, and integration with host neuronal circuits in the brains of normal and neonatal thymus-less rats, which represent important research advances in the integration of cerebral organoids with neural circuitry in the host brain [12] (Fig

High levels of tumor GST and GT expression were employed to selectively target tumor with GST- or GT-activated drugs