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This included circumvention of the complex downhill syndrome, as well as a sudden decrease of blood supply, decreased NO levels in the inferior caval vein tissue, an immediate heavy loss of endothelial cells from the vascular wall, a lower eNOS production ability (Berra-Romani et al., 2013), and finally, the elimination of oxidative stress due to endothelial cell lysis (Rangan and Bulkley, 1993

Furthermore, the combined deficits in Se and Zn may worsen thyroid dysfunction by restricting the synthesis of hormones and the enzymatic conversion of T4 to T3

Journal of Neurochemistry, 77 , 519529

Grossman W
