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Doctors often suggest this for adults with B12 deficiency or those at risk

Ensuring that you're getting enough of each vital component your body needs to thrive is key
More NAD+ boosts SIRT1 activity

Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease
