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Some studies estimate that absorption may be as low as 1.3% from a 1000mcg dose, which is why you are likely to see supplements offering high doses
Of course, take manufacturer or prescriber guidance for route
Cells 9:167 Jelinek T, Sevcikova T, Popkova T, Cerna L, Broskevicova L, Brozova L et al (2020) Limited efficacy of daratumumab in multiple myeloma with extramedullary disease
