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The EpsteinBarr virus is of particular interest as it latently infects and immortalizes B lymphocytes, driving their persistence in an activated state and possibly contributing to MS pathogenesis by generating a pro-inflammatory milieu and forming ectopic lymphoid follicles in the CNS 29,30

This effect was blocked by chlorpromazine, suggesting that this effect was driven by D2-like receptors, although the effect could be influenced by the many effects of chlorpromazine on nondopaminergic receptors (Yang, Anh et al., 2014)

Serum vitamin B12 is the most common way to measure your vitamin B12 status (11)

In March 2025 it will be a year since the Nice Guideline on B12 Deficiency in over 16s was published