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Description
Following immediate effects, symptoms displaying systemic toxicity are manifested as generalized prostration, fatigue, weakness, dizziness, loss of coordination and ataxia
640 In addition, under physiological conditions, zinc binds preferentially to MT, further activating MT to exert its anti-oxidative stress function
It can inhibit a key step of the folate cycle (at the level of 5-methyltetrahydrofolate), leading to the accumulation of AICAR a natural analog of AMP that potently activates AMPK
Norman PH, Vaporciyan AA, Rice DC , Correa AM
