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In the 3-KO and WT groups, male mice aged 1214 weeks were divided into three subgroups including: saline control, AOD9604 administered at a dose of 250 g/kg/day, and hGH administered at a dose of 1 mg/kg/day

In the pivotal 2018 animal study by Neelakantan et al., systemic treat Mechanism of Action 5-Amino-1MQ inhibits NNMT (nicotinamide N-methyltransferase), an enzyme that catalyzes the N-methylation of nicotinamide using S-adenosylmethionine (SAM) as the methyl donor, producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH) as products

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Get bloodwork every 8 to 12 weeks