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However, its effect in vivo is very likely not direct but due to its ability to modulate the cells antioxidant defense mechanisms
Addressing blood-brain barrier impairment in Alzheimers disease

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Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ (1996) Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
