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Description
The hydrophobic staple motif consists of a specific i,i+5 hydrophobic interaction between a residue (N) that precedes the N-cap residue and a residue (N4) located within the 6-helix

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It is created by the liver and is used by several bodily functions

The product was added to the solution of KOH (2.2 g, 40 mM) in H 2 O:methanol 1:1 (40 ml), and heated at reflux for 3 h
