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doi: 10.1186/s12893-015-0075-4 122 ChengYDiSFanCCaiLGaoCJiangPet al
5), suggesting that AKT and MEK mutually repress each other
Potential short-term systemic effects may include: Facial flushing Warmth or vasodilatory sensation Lightheadedness Increased heart rate Temporary discomfort Why it matters: These effects are not just theoretical
Likewise, sex differences in the way some of these drugs are absorbed and metabolized has been noted 37 , though we did not observe any differences in L2-Cmu PK or exposure levels between male and female animals
