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This triggers sustained activation of NF-B and STAT3 pathways, driving the production of proinflammatory cytokines (IL-6, TNF-, and IL-1) that fuel hyperproliferation and apoptosis resistance in epithelial tissues (Wang X

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As a crucial second messenger within granulosa cells, MI is central to transducing FSH signals, favoring the selection of the dominant follicle, and supporting oocyte development throughout oogenesis