most common place for melanotic macule a at the wet–dry line of the lower lip. b Melanotic Pigmented Oral Lesions: Clues to

Het effect is dosis-afhankelijk en reversibel (na staken trekt de pigmentatie binnen weken tot maanden weg)

The specificity of MITF is low and this limits its use in the differential diagnosis of mimickers of melanocytic lesions

Lipid metabolism is thought to be the central metabolic pathway among mycobacterial species ( Mtb infects the macrophages by exploiting their phagocytic nature and is able to persist the infection in a state of dormancy by forming granulomas within the host ( Mtb contains four closely related genes encoding putative PLCs

285 , 288 Of note is that these SVR rates are higher than occurs in persons without kidney disease treated with standard interferon alone