glutathione reductase activity in oxidative stress system enhancement for cardiac protection: pharmacological options against and ferroptosis Mathematical model for glutathione dynamics
Description
Le glutathion est compos de trois acides amins essentiels : la cystine, l'acide glutamique et la glycine
Aldosterone/salt-induced hypertension in rats results in renal damage and an increase in the production of ROS in the renal cortex (69)
The reaction formula can be summarized as follows: 2 GSH GSSG + 2H + 2e (under the action of GPX or ROS) However, to prevent GSSG accumulation from disrupting the intracellular sulfhydryl balance, cells need to rapidly convert it back to GSH through an efficient reduction system
Swapnil P, Meena M, Singh SK, Dhuldhaj UP, Harish, Marwal A
