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Consistent with this overall concept is the finding that in yeast, the FMN-dependent quinone reductase Lot6 has been shown to act as a redox switch which senses oxidative stress and modulates the binding of the transcription factor Yap4 to the 20s proteasome (Sollner et al., 2009)

This interaction is critical for researchers studying the ileal brakea feedback mechanism that inhibits upper gastrointestinal motility

doi: 10.1073/pnas.2016818118 131 HagenFLumbschHTArsic ArsenijevicVBadaliHBertoutSBillmyreRBet al

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