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RBCs RBCs are the cell type most sensitive to oxPPP loss

At the immune and inflammatory interface, polyamines suppress NF-B p65 translocation and attenuate PI3KAKT and MAPK activation, reducing inducible nitric oxide synthase (iNOS) and COX-2 expression and the subsequent production of NO, prostaglandin E 2 (PGE 2 ), and cytokines such as TNF-, IL-1, and IL-6 [229]

Dumyati G, Concannon C, van Wijngaarden E, Love TM, Graman P, Pettis AM, Greene L, El-Daher N, Farnsworth D, Quinlan G, Karr G, Ward L, Knab R, Shelly M American journal of infection control

Lu K, Chen X, Liu W, Zhang Z, Wang Y, You K, Li Y, Zhang R, Zhou Q