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Description
Recent studies have shown that FSP1 effectively prevents ferroptosis caused by GPX4 deletion or inhibition, and its expression increases when GPX4 expression is reduced
Oxidative stress and accelerated aging are the clearest targets, since glutathione is the front-line molecule that neutralizes free radicals before they damage mitochondria and DNA
Glutathione levels naturally decline with age, stress, poor diet, and environmental toxin exposure
Mol Carcinogenesis (2015) 54:151320
