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Under hypoxic conditions, human macrophages inhibit ferritin autophagy by reducing the expression of nuclear receptor coactivator 4 (NCOA4), resulting in increased mitochondrial ferritin expression and decreased intracellular free iron, thus regulating ferroptosis [35]

For example, gender may be relevant, given males report greater improvements in cholesterol levels than females

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Carmona-Bayonas A, Caldern C, Hernndez R, Fernndez Montes A, Castelo B, Ciria-Suarez L, et al