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Fluoride has been identified as an inhibitor of SAH hydrolase.[165] Several reports have indicated that fluoride exposure can reduce the cellular level of GSH and induce oxidative stress in liver, kidney, heart, spleen, and brain.[5,15,19,225,227] Oxidative stress, which can stimulate microglial activation and immunoexcitotoxicity, may lead to neurodevelopmental abnormalities in children by affecting numerous cellular processes, especially via cell signaling and mitochondrial dysfunction

The anti-aging benefits of gold can be traced back 5,000 years to Cleopatra, who was rumored to have slept in a gold mask to enhance her legendary beauty

[DOI] [PubMed] [Google Scholar] 266.Kamal A.M., Abd El-Fatah A.S., Rizk M.M., Hassan E.E

When more free radicals than antioxidants are present, oxidative cell damage occurs