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And while the MTHFR variants primarily impact folate metabolism, the interconnectedness of the methylation cycle means that it indirectly affects vitamin B12 utilization as well

Vitamin B is an essential nutrient that is helpful in effectively performing various body functions like maintaining healthy nerve tissues, brain function, and red blood cell production

Some B12 supplements may also include aluminum, which is more likely to build up in the body when someone has kidney disease

**Additional tests and blood work may be needed How to self-inject peptides
