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The question is how confidently those effects translate to humans at the doses being used, through the delivery routes being used, over the time periods being used

in other cases, toxic effects of l-Cys on the nervous system have also been reported (oxidized l-Cys derivatives or compounds such as cysteine alpha-carbamate caused neuronal degeneration) [78]

Studies have shown significant upregulation of NADPH oxidase and downregulation of SOD in CKD, implying that an increase in superoxides is associated with oxidative stress in renal insufficiency [9]

10.1016/j.joca.2020.01.007 [DOI] [PubMed] [Google Scholar] Zhang J., Hu W., Ding C., Yao G., Zhao H., Wu S