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The occurrence of ADPKD is primarily attributed to mutations in the Pkd1 gene or Pkd2 gene, which, respectively, encode polycystin 1 (PC1) and polycystin 2 (PC2) (Luo et al., 2023a)

Un pas fascinante Entre las numerosas regiones fascinantes que atraen con razn a todos los extranjeros y turistas a quien les gusta lo folklrico y singular, existe un pequeo pas poco conocido pero no menos curioso e interesante

Design and activity of specific hypoxia-inducible factor-2 (HIF-2) inhibitors for the treatment of clear cell renal cell carcinoma: discovery of clinical candidate ( S )-3-((2,2-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H -inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385)