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Mutations in the deubiquitinase gene USP8 cause Cushings disease
Clinical studies have shown that growth hormone activates osteoblasts and stimulates bone remodeling in older men, women, and postmenopausal patients with OP but has no long-term effects on the spine and proximal femur bone density (Rudman et al., 1990

Dopaminergic imaging and clinical predictors for phenoconversion of REM sleep behaviour disorder

This greatly simplifies the extent of biological tools needed and improves genetic efficiency for drug metabolism while maintaining a broad reactivity and substrate scope