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Biotech Histochem 1995, 70 (5), 220233

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361 Clinical studies have shown that elevated serum ATX levels in patients with liver fibrosis and cholestasis-associated pruritus correlate with fibrosis severity and poor overall survival

At the cellular level, thiol antioxidants induced apoptosis in transformed cell lines but not in normal cells, suggesting that direct redox control of p53 may be influential in determining cell fate under stress conditions [28]