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Biochim Biophys Acta 1804:662667 Axarli I, Muleta AW, Vlachakis D, Kossida S, Kotzia G, Maltezos A, Dhavala P, Papageorgiou AC, Labrou NE (2016) Directed evolution of Tau class glutathione transferases reveals a site that regulates catalytic efficiency and masks co-operativity
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They support communication between cells and have been reported to help regulate many biological processes
Nevertheless, gaining specific control over both types of IRE1 activities remains a major challenge for therapeutic strategies
